In 2007, Scott joined the St. George Illawarra Dragons. In 2009, he played for Country in the City vs Country match due to an injury to another player. Scott was ruled out for the 2010 match after being named as 18th man for Australia. He was selected for New South Wales in Game 2 of the 2010 State of Origin series. His debut was subject to media-wide publicity, as he was the subject of a racial controversy involving their assistant coach Andrew Johns. Johns had allegedly made a racial comment in reference to Queensland centre Greg Inglis, while talking to Scott about tackling him, which triggered teammate Timana Tahu's exit from the New South Wales camp. Scott also played in Game 3. He played in the Dragons' 2010 NRL Grand Final-winning team defeating the Sydney Roosters, starting in the second-row. He also played in the 2011 World Club Challenge-winning team against the Wigan Warriors. In 2011, Scott was selected as 18th man for Australia in the 2011 ANZAC Test to play New Zealand. He was selected for 2 games of the 2011 State of Origin series. Scott made his debut for the Kangaroos in November against Wales in the 2011 Four Nations tournament. On 9 March 2012, Scott signed a 4-year contract with the Newcastle Knights starting in 2013 to rejoin former Dragons coach Wayne Bennett. He played in Game 3 of the 2012 State of Origin series after Glenn Stewart was ruled out. Scott played 118 games over six seasons with the Dragons between 2007–2012.